Template-Type: ReDIF-Article 1.0 Title: Towards a risk classification for tumor lysis syndrome in solid neoplasms Author-Name: Rodríguez, José Grabiel Correa Author-Name: Martínez, Leonardo Manuel Castell Author-Name: Fiqueredo, Nadia del Rosario Blanco Abstract: Introduction: Tumor lysis syndrome in solid tumors is a rare complication associated with high mortality. Its exclusion from clinical practice guideline risk classifications, as well as its underestimation, exacerbates this gap. Objective: To propose hypotheses for a risk classification model for tumor lysis syndrome in solid tumors. Development: Risk classification for tumor lysis syndrome in solid tumors should include three categories: high, intermediate, and low. In addition, there are factors that can increase the risk, such as metastatic burden, elevated lactate dehydrogenase levels, pre-existing renal and/or hepatic impairment, and disseminated intravascular coagulation. Conclusions: Although traditionally considered low-risk, tumor lysis syndrome in solid tumors should be addressed with classification models that allow for its appropriate stratification in daily clinical practice. Journal: SAP Health and Policy Year: 2026 DOI: 10.62486/shp2026326 File-URL: https://southam.pub/journals/files/shp/shp2026326en.pdf File-Format: application/pdf Handle: RePEc:cwf:shpart:shp2026326