Template-Type: ReDIF-Article 1.0
Title: Comparative Efficacy of Tranexamic Acid Versus Vitamin C in the Treatment of Melasma with Microneedling
Author-Name: Aguilera, Denisse Díaz
Author-Name: Pérez, Kendry Morales
Author-Name: Aguilera, Linet Laura Díaz
Author-Name: Ferras, Sara Mosquera
Abstract: Melasma is a common pigmentary dermatosis in women that affects quality of life and is resistant to conventional treatments. This study analyzed the efficacy of tranexamic acid and vitamin C (ascorbic acid), associated with microneedling, in a sample of six women drawn from a population of 10 candidates. Variables such as age, lesion evolution time, number of sessions, and clinical differences between both treatments were evaluated. The results indicated a significant reduction in the melanin index in both groups, with moderate statistical superiority in the tranexamic acid group. Mechanisms of action, limitations, and clinical recommendations are discussed.
Journal: SAP Primary Care
Year: 2026
DOI: 10.62486/pc2026123
File-URL: https://southam.pub/journals/files/pc/pc2026123en.pdf
File-Format: application/pdf
File-URL: https://southam.pub/journals/files/pc/pc2026123es.pdf
File-Format: application/pdf
Handle: RePEc:cwf:pcarti:pc2026123